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However, such assistance is prohibitively expensive and unsuccessful in half of patients.ġ0,11 Contrary to popular belief, sensory loss does not eliminate sexual capacity. This has improved in 2003 to an approximately 51% pregnancy rate in those whi seek to reproduce including extensive medical assistance. 1,10 Reproductive assistance techniques have greatly improved in recent history: fewer than 1% of men with SCI in 1960 became fathers via intercourse. More than 80% of patients with SCI are male, and the majority of those are young men of reproductive age who may not have had the opportunity to have a family yet, causing even more psychological stress. One physical symptom that causes male patients much psychological stress, yet remains largely understudied, is the development of infertility. SCI elicits pathological changes to the gastrointestinal and urinary tracts, loss of bone density, muscle atrophy, neuropathic pain, autonomic dysfunction, sleep disturbances, and increased pulmonary complications.ģ-9 In addition to the physical ailments, patients with SCI commonly experience marital stress, job loss, depression, and other psychological and social issues semi-unique to each patient. 1,2 Although sensory and motor loss are the signature symptom of this injury, these represent only a fraction of the negative consequences of SCI. Spinal cord injury (SCI) affects up to 12,000 new patients in the United States every year. Loose, PhD, Department of Integrative Biology and Pharmacology, UTHealth, 6431 Fannin Street, MSB 4.130, Houston, TX 77030, E-mail: 1 Department of Integrative Biology and Pharmacology, UTHealth, Houston, Texas.Īddress correspondence to: David S. 2 Department of Molecular Physiology and Biophysics, Baylor College of Medicine, Houston, Texas.ĭavid S.

2 Department of Molecular Physiology and Biophysics, Baylor College of Medicine, Houston, Texas. 1 Department of Integrative Biology and Pharmacology, UTHealth, Houston, Texas.Ĭhristine Beeton.

1 Department of Integrative Biology and Pharmacology, UTHealth, Houston, Texas.

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